US FDA approved of XHANCE as the first and only medication for adults with chronic rhinosinusitis without nasal polyps. It is a fluticasone propionate nasal spray which uses the Exhalation Delivery System to enable topical steroid to the inflamed areas and is proven effective.

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https://ir.optinose.com/news-releases/news-release-details/xhance-approved-fda-first-and-only-medication-indicated